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Proof of principle:

Golden Lancet Oncol 2015

Response

Abscopal response: 11/41 (26.8%)

Survival

Improved OS in responders

Ø

¼ of the patients with abscopal effect

Ø

Improved OS in patients with abscopal effect

07.09.17

ESTRO SBRT COURSE 2017 - Matthias Guckenberger

33

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• Palliative RT in 61%; SRT in only 25%

Ø

Tx-related pulmonary toxicity: (n=3) vs (n=1)

07.09.17

ESTRO SBRT COURSE 2017 - Matthias Guckenberger

34

Prior RT

42 (43%)

PFS

OS

Shaverdian Lancet Oncol 2017