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• Radiotherapy established anti-inflammatory and
immune-supressive treatment
Radiotherapy – a double sided sword
07.09.17
ESTRO SBRT COURSE 2017 - Matthias Guckenberger
25
Total body / morrow irradiation Painful heel spur irradiation
Ø
Systemic immunosupression
Ø
Local anti-inflammatory
/ 07.09.17
ESTRO SBRT COURSE 2017 - Matthias Guckenberger
26
Immuno-RT – new OARs to consider ?
• Low-dose spread to lymphaytic system (circulating
blood, lymph nodes, bone marrow) to be considered
Proportion of circulating
lymphocytes inativated
(>0.5%) by liver SBRT
Basler, Tanadini submitted
12%
6%
19%
22%
6 cm
7 cm