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INFORMS Philadelphia – 2015

264

4 - Integrated Variable Importance Assessment in Multi-stage

Manufacturing Processes

Gianluca Gazzola, Rutgers Center for Operations Research,

100 Rockafeller Road, Piscataway, NJ, 08854, United States of

America,

ggazzola@scarletmail.rutgers.edu

, Jeongsub Choi,

Myong K (MK) Jeong, Byunghoon Kim

We introduce a method for the assessment of variable importance in

manufacturing processes characterized by a hierarchy of technical relationships

between stage variables. Regression models of direct technical relationships and a

novel permutation measure are employed to quantify the local contribution of

every variable. Global contributions are finally obtained by integrating these local

assessments, based on the overall structure of indirect and direct technical

relationships in the process.

TA19

19-Franklin 9, Marriott

Computational Integer Optimization

Sponsor: Computing Society

Sponsored Session

Chair: Yan Xu, Director, SAS, 100 SAS Campus Dr., Cary, NC,

United States of America,

yan.xu@sas.com

1 - Recent Advances in the FICO Xpress MIP Solver

Michael Perregaard, Xpress Team, FICO, International Square,

Starley Way, Birmingham, B37 7GN, United Kingdom,

MichaelPerregaard@fico.com

We will present some of the recent MIP advances in the FICO Xpress solver, with

an emphasis on how it is able to exploit the ever increasing core counts of

modern CPUs.

2 - The SAS MILP Solver: Current Status and Future Developments

Philipp Christophel, SAS Institute Inc., 100 SAS Campus Dr.,

Cary, NC, 27607, United States of America,

Philipp.Christophel@sas.com,

Menal Guzelsoy, Imre Polik,

Amar Narisetty

We give an overview of the current status of the SAS mixed integer linear

programming (MILP) solver that is part of the SAS/OR product. The focus will be

on describing recent implementation efforts for the MILP presolver as well as

future development directions.

3 - Performance Improvements and New Features in the

Gurobi Optimizer

Chris Maes, Senior Developer, Gurobi Optimization, Inc., 125

Beacon St, Apt. #4, Boston, MA, 02116, United States of America,

maes@gurobi.com

This talk will cover the latest developments in the Gurobi Optimizer. We’ll discuss

the new Gurobi Cloud, which makes it easy to launch one or more Gurobi

machines when you need them. We’ll also talk about our upcoming release,

which includes significant performance enhancements and several new features.

4 - CPLEX Keeps Getting Better

Andrea Tramontani, CPLEX Optimization, IBM Italy, Via Martin

Luther King 38/2, Bologna, Italy,

andrea.tramontani@it.ibm.com

We present some of the new features and algorithmic techniques that have been

recently added to IBM ILOG CPLEX Optimizer, and we give detailed benchmark

results that demonstrate the performance improvements achieved in latest CPLEX

versions.

TA20

20-Franklin 10, Marriott

Cloud Services and Applications

Cluster: Cloud Computing

Invited Session

Chair: Grace Lin, Data Analytic Technology and Applications (DATA),

Data Analytic Technology and Applications (DATA), Taipei, Taiwan -

ROC,

gracelin@iii.org.tw

1 - Revealing Power Structures through Novel

Biclustering Approaches

Sabine Baumann, Professor Dr., Jade University, College of

Mgmt, Info., Tech., Friedrich-Paffrath-Str. 101, Wilhelmshaven,

22880, Germany,

sabine.baumann@jade-hs.de

, Oliver Eulenstein,

Christoph Wunck

Cloud and big data provide unprecedented access to massive interaction networks

of people and organizations. However, exploring such rich data environments

encounters equally extensive challenges: unreliable, incomplete or distorted

information, or computational limitations. We recover missing interactions from

vast corporate networks using novel biclique clustering techniques to detect the

most significant edges, and hence provide new insights into power structures.

2 - Running Your Optimization Model on the Cloud with the IBM

CPLEX Studio IDE

Frederic Delhoume, Software Engineer, IBM, 9 Rue de Verdun,

Gentilly, 94253, France,

delhoume@fr.ibm.com

We will show how to easily run optimization models from the IBM CPLEX Studio

IDE. We will also demonstrate how to monitor the cloud service and get local

results from the remote optimization service. A REST API way of running models

on the cloud will be shown.

TA21

21-Franklin 11, Marriott

Medical Decision Making in Cancer Care

Sponsor: Health Applications

Sponsored Session

Chair: Christine Barnett, University of Michigan, 1205 Beal Ave.,

Ann Arbor, MI, United States of America,

clbarnet@umich.edu

1 - Predictive Modeling for Optimal Design of Cancer

Detection Protocols

Selin Merdan, University of Michigan, 1205 Beal Avenue,

Ann Arbor, MI, 48109, United States of America,

smerdan@umich.edu,

Brian Denton

Diagnosis of chronic diseases often involves expensive and invasive tests and

procedures. Predictive models can play an important role in determining the

optimal diagnostic protocol based on individual patient risk factors. We discuss an

approach for developing predictive models using clinical observational data that

suffers from common sources of bias such as low disease prevalence and missing

data. We illustrate the use of these models for optimization of prostate cancer

diagnostic protocols.

2 - Model-based Calibration for Natural History Modeling

Jing Voon Chen, University of Southern California, Epstein Dept

of Indus & Sys Eng, Los Angeles, CA, United States of America,

jingvooc@usc.edu

, Julie Higle

A natural history (NH) model often requires calibration of unobservable model

parameters to fit observed data. Uncertainty in the data and in the calibrated

parameters impacts confidence in the optimal decision. We propose a method for

model-based calibration that is resilient to these uncertainties, especially for

comparative analyses of disease screening or treatment strategies. Illustrative

examples and sensitivity analyses will be discussed.

3 - Assessment of Individualized Human Papillomavirus (HPV)

Vaccination Strategies

Fan Wang, University of Arkansas, 4207 Bell Engineering Center,

Fayetteville, AR, United States of America,

fxw005@email.uark.edu

, Shengfan Zhang

The human papillomavirus (HPV) is the most common sexually transmitted virus

in the U.S. To prevent multiple cancers attributable to the HPV, HPV vaccine is

recommended for preteens and teens who have not been exposed to HPV. We

develop a simulation model for the optimal design of personalized HPV

vaccination program, which incorporates multiple social-behavioral and

demographic risk factors. The efficacy of the HPV vaccination program is

evaluated in terms of the HPV-related health outcomes.

4 - Tailoring CRC Screening Strategy for Different Age- and

Gender-specific Population Subgroups

Carolina Vivas, Purdue University, West Lafayette, IN 47906,

United States of America,

cvivas@purdue.edu

, Nan Kong, Robert

Klein, Thomas Imperiale

Standard guidelines for colorectal cancer (CRC) strategies do not consider

different age- and gender-specific subgroups for tailored screening

recommendations. Recent evidence suggests that men tend to face a higher risk of

developing advance adenomas earlier than women. We apply Design of

Experiments techniques to quantify the risk differences on CRC disease

progression. Model based cost-effectiveness analyses of various screening

strategies are conducted for different population subgroups.

TA19