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INFORMS Nashville – 2016

147

3 - Price Competition And Direct-to-consumer Advertising In

Prescription Drug Markets

Abhik Roy, Professor, Quinnipiac University, Department of

Marketing, School of Business (SB-DNF), Hamden, CT, 06518-

1949, United States,

abhik.roy@quinnipiac.edu

Mary Schramm

We examine the relationship between direct-to-consumer advertising (DTCA),

and interdependent pricing among firms marketing competing drugs to patients

within the same therapeutic area. We propose that DTCA is a coordinating

mechanism, where a firm signals its willingness to be a Stackelberg price leader by

spending heavily on advertising promoting the drug formulation, not just its own

brand within the category. Propositions are developed about the impact of ad

effectiveness, ad spending and substitutability on the occurrence of a Stackelberg

system. Evidence to support these propositions is provided through empirical

analysis of data from a number of prescription drug categories.

4 - A Dominant Retailer’s Strategic Response To More Efficient

Weak Retailer

Ehsan Bolandifar, Assistant Professor, Chinese University of Hong

Kong, 9/F, Cheng Yu Tung Buliding, No., 12, Chak Cheung Street,

Shatin, N.T., Hong Kong, 999077, Hong Kong,

ehsan@baf.cuhk.edu.hk

, Zhong Chen, Fuqiang Zhang

We construct a multi-stage model to study the strategic interaction between

national brand manufacturer, a dominant and weak retailers. We show that more

efficiency on the weak retailer’s end makes the dominant retailer reduce its joint

advertisement level for the national brand and offers lower market prices, while it

also receives a discount form the national brand manufacturer. We also show that

manufacturer does not always benefit from improvement in its operational

efficiency of its retailers. Similarly, dominant retailer does not always benefit from

cheaper store brand procurement costs.

5 - Direct Sales, Agent Selling or Reselling? Firms’ Channel Structure

With Consumers’ Channel Preference

Libo Sun, PhD Student, University of Science and Technology of

China, 96# Jinzhai Road, Hefei, Anhui, PR China, Hefei, 230026,

China,

libosun@mail.ustc.edu.cn

, Yugang Yu

Numerous firms exert themselves to adopt multiple channels to sell products.

However, even when facing identical products, consumers’ choices among these

channels could be diverse due to channel preference. We use a stylized theoretical

model to answer two key questions faced by a monopoly manufacturer: (1) how

does consumers channel preference (CCP) affect its channel structure, namely,

when should the manufacturer choose a sin-gle-channel and when should it

adopt a dual-channel instead? Furthermore, should the manufacturer choose an

independent reseller or an agent platform when it intends to leverage external

force? We respectively derive the manufacturer’s optimal channel deci-sions

when consumers show positive and negative CCP to the manufacturer’s direct

channel. We find that: (1) compared with centralized case, the manufacturer

prefers to adopt dual-channel in a larger area in decentralized case; (2) the

manufacturer will choose a dual-channel either when consumers’ CCP to direct

channel is positive or negative enough; (3) the exact forms of dual channel

depends on the thresholds of the agent fee charged by the platform.

MA94

5th Avenue Lobby-MCC

Technology Tutorial: MathWorks/Artelys

Technology Tutorial

1 - MathWorks: Data Analytics With MATLAB

Mary Fenelon, MathWorks, Natick, MA,

United States,

mary.fenelon@mathworks.com

MATLAB has evolved to become a platform for predictive and prescriptive

analytics. Engineering, Finance, Data Science, and IT teams are using MATLAB to

build today’s advanced analytics systems ranging from risk analysis to predictive

maintenance and telematics to advanced driver assistance systems and sensor

analytics. Join us to see how MATLAB can help you: • Access, explore, and

analyze data stored in files, on the web, and from data warehouses • Clean,

explore, visualize, and combine complex multivariate data sets • Prototype, test,

and refine predictive models using machine learning methods • Build and solve

prescriptive models and analyze results • Share your results with others We’ll

highlight our newest features for Big Data, machine learning, deep learning, and

optimization through examples such as load forecasting, Monte Carlo simulation,

predictive maintenance, and embedded sensor analytics.

2 - Artelys: Solving Large Least-Squares Models With The Artelys

Knitro Nonlinear Optimization Solver

Richard Waltz, Artelys, 150 N Michigan Avenue, Suite 800,

Chicago, IL, 60601, United States,

Richard.waltz@artelys.com

Artelys Knitro is the premier solver for nonlinear optimization problems. This

software demonstration will highlight the latest Knitro developments, including a

new specialized API, as well as enhanced algorithms, for large-scale nonlinear

least-squares models. We will demonstrate how to solve least-squares models

using Knitro through a variety of interfaces such as R, MATLAB and C/C++, and

also provide some benchmarking results. In addition, we will summarize some of

the other recent developments in Knitro.

Monday, 10:00AM - 10:50AM

Monday Plenary

Davidson Ballroom-MCC

Philip McCord Morse Lecture: Margaret L. Brandeau

Plenary Session

Chair: Mike Magazine, University of Cincinnati, Cincinnati, OH

45221-0130,

mike.magazine@uc.edu

1 - Public Health Preparedness: Answering (Largely Unanswerable)

Questions With Operations Research

Margaret Brandeau, Stanford University, Stanford, CA,

United States,

brandeau@stanford.edu

Public health security - achieved by effectively preventing, detecting, and

responding to events that affect public health such as bioterrorism, disasters, and

naturally occurring disease outbreaks - is a key aspect of national security.

However, effective public health preparedness depends on answering largely

unanswerable questions. For example: What is the chance of a bioterror attack in

the United States in the next five years? What is the chance of an anthrax attack?

What might be the location and magnitude of such an attack? This talk describes

how OR-based analyses can provide insight into complex public health

preparedness planning problems - and thus support good decisions.

Monday, 11:00AM - 12:30PM

MB01

101A-MCC

Data Mining Under Uncertainty

Sponsored: Data Mining

Sponsored Session

Chair: Erhun Kundakcioglu, Ozyegin University, Nisantepe District

Orman Street / Cekmekoy, Istanbul, 34794, Turkey,

erhun.kundakcioglu@ozyegin.edu.tr

1 - Approximation Algorithms For Solving Large-scale

Classification Problems

Neng Fan, University of Arizona,

nfan@email.arizona.edu

To deal the classification of data with uncertainties, the distributionally robust

optimization models are proposed for the support vector machines. First the

problems are reformulated as semidefinite programs or second order cone

programs. To solve these problems on large-scale data sets, we design a stochastic

subgradient algorithm. The numerical experiments will be presented to show the

efficiency of our algorithms.

2 - Margin Maximization Via Benders Decomposition To Solve

Multiple Instance Learning Problems

Emel Seyma Kucukasci, Istanbul Commerce University,

Istanbul, 34840, Turkey,

eskucukasci@ticaret.edu.tr

Emel Seyma Kucukasci, Bogazici University, Istanbul, 34342,

Turkey,

eskucukasci@ticaret.edu.tr,

Mustafa Gokce Baydogan

Multiple instance learning (MIL) aims to solve classification problem where bags

of instances form the input data. Margin maximization model of MIL classification

is a MINLP problem. We develop a Benders decomposition algorithm for MINLP

solution to deal with large datasets. A hybrid approach combining Benders

decomposition and bagging procedure is proposed to test the generalizability of

the results. Computational results on publicly-available molecular activity

prediction, image annotation and text classification datasets are also provided.

MB01