1681 / 2063
ESTRO
2017
Combined chemo- and radiotherapy treatment:
Cellular / molecular interaction
DNA damage Chromosome Cell
Apoptosis
induction repair
aberration Cycle
5-Fu
MTX
HU
dFdC
F-ara-A
-
?
?
-
-
-/+
?
-/+
-
-
-
?
+
+
+
+
?
+
+
+
?
?
?
-
-?
Antimetabolites
ESTRO
2017
DNA damage Chromosome Cell
Apoptosis
induction repair
aberration Cycle
Cis-platinum
BCNU
Cyclophosphamide
+?
?
?
+
+
?
?
-
-
-
?
?
?
?
?
Alkylating agents
Combined chemo- and radiotherapy treatment:
Cellular / molecular interaction