1680 / 2063
ESTRO
2017
EFFECT F-ara-A ON CHROMOSOME BREAK
REPAIR AFTER SINGLE DOSE IRRADIATION
(4 Gy) IN HUMAN LYMPHOCYTES
20
40
60
80
100
0 20 40 60 80 100
PERCENT OF INITIAL
DAMAGE
TIME AFTER IRRADIATION (min.)
From Jayanth et al.
RT alone
F-ara-A (100 µM)
0.5 h prior to RT
ESTRO
2017
CELL CYCLE REDISTRIBUTION INDUCED
BY FLUDARABINE (800 mg/kg) IN SA-NH TUMOR
DNA CONTENT
0 h
3 h
6 h
12 h
15 h
18 h
24 h
36 h
BrdUrd CONTENT