AOAC ISPAM Stakeholder Panel Meeting Book 3-14-17

PRECISION CHALLENGES

SMPR CHALLENGES - PRECISION

• Method precision depends on sample

homogeneity, particle size, test portion size,

and extraction solvents/conditions.

• Pre-extraction preparation of samples

(grinding/homogenizing) will be critical for

managing variation.

• Test portion sizes may be larger than usual

• RSD criteria may be dependent on mean

• RSD Criteria for oats may be larger than

usual, even for ELISA methods