Diagnostic preparations 1309
Interleukin-2:
Increased risk of delayed
reactions. Monitor closely.
Beta blockers:
Atypical anaphylaxis. Monitor
closely.
Neuroleptics and phenothiazine derivative
antidepressants:
Reduce seizure threshold.
Should be discontinued 48 hours prior to
and not resumed for 24 hours following
procedure.
Nephrotoxicdrugs:
Administration shouldbe
delayed until media has cleared the body.
Thyroid function tests may be reduced
for
up to several weeks.
Contraindications
Contraindicated in individuals with known
hypersensitivity to the preparation or
a history of serious hypersensitivity to
iopromide or iodine-containing contrast
media.
care considerations
• Closelymonitor individualfordevelopment
of anaphylactic reaction. Ensure emergency
management equipment is available and in
correct working order.
• Monitor vital signs and renal function
closely following procedure.
• Ensure the person is well-hydrated before
and after the procedure to avoid contrast-
induced nephropathy.
• Assess mental status.
• Ensure safety if the person is light-headed.
• Thyroid function testsmay be reduced for
up to several weeks.
Patient teaching
• Advise person to report any adverse
effects.
• Advise person to take care when standing
up or getting out of bed due to potential
dizziness.
ioversol
Optiray
Pregnancy risk category B1
Use in sport: Permitted
Available forms
Vial:
339 mg/mL in 50 mL, 100 mL; 509 mg/
mL in 30 mL, 50 mL, 100 mL, 200 mL;
678 mg/mL in 20 mL, 30 mL, 50 mL, 75 mL,
100 mL, 150 mL; 741 mg/mL in 20 mL,
30mL,50mL,75mL,100mL,150mL,200mL
Prefilledsyringe:
509mg/mL in 50mL, 125mL;
678mg/mL in50mL,75mL,125mL;741mg/
mL in 30 mL, 50 mL, 75 mL, 100 mL, 125 mL
Indications & dosages
➤
X-rayorCTcontrastmedium—
Adults:
Individualised according to indi
vidual factors and nature of X-ray or CT scan.
Action
Non-ionic iodinated radiographic contrast
medium for angiographic and urographic
examinations.
Route Onset
Peak
Duration
IV
Immediate Unknown Unknown
Adverse reactions
CNS:
cerebralinfarction
,
coma
,
convulsions
,
dizziness, dysphasia, headache, restlessness,
palpitations, paraesthesia, paralysis, shaking,
syncope, vertigo.
CV:
anginapectoris,arrhythmia,bradycardia,
conduction defect, cyanosis,
disseminated
intravascular coagulation
, false aneurysm,
hypertension, hypotension,
shock
,
throm
bosis
, thrombophlebitis, vascular spasm,
vascular trauma, vasodilation.
Eye:
altered vision, blurred vision, periorbital
oedema.
GI:
altered taste, nausea, vomiting.
GU:
temporaryanuria,nephropathy,
nephro
toxicity
.
Musculoskeletal:
muscle spasm.
Psychiatric:
disorientation, hallucination.
