1306 Miscellaneous drug categories
Reactions may be
common
, uncommon,
life-threatening
, or
commonandlife-threatening.
• Ensure the person is well-hydrated before
and after the procedure to avoid contrast-
induced nephropathy.
• Observe for signs of lactic acidosis.
• Assess mental status.
• Ensure safety if the person is light-headed.
• Thyroid function testsmay be reduced for
up to several weeks.
Patient teaching
• Advise person to report any adverse
effects.
• Advise person to take care when standing
up or getting out of bed due to potential
dizziness.
iomeprol
Iomeron
Pregnancy risk category B3
Use in sport: Permitted
Available forms
Solution for injection:
180 mg iodine/mL in
15 mL; 300 mg, 350 mg, 400 mg iodine/mL
in 20 mL, 50 mL, 100 mL, 200 mL
Indications & dosages
➤
X-rayorCTcontrastmedium—
Adults:
Individualised according to
individual factors and nature of X-ray or
CT scan.
Action
Non-ionic iodinated radiographic contrast
mediumforvascular,renalandothersystems.
Route Onset
Peak
Duration
IV
Immediate Unknown 96 hrs
Adverse reactions
CNS:
altered taste sensation, dizziness, dry
mouth, headache, hemiplegia, hypertonia,
hypotonia, nervousness, neuropathy,
paraesthesia, somnolence, syncope.
CV:
anginapectoris,arrhythmia,bradycardia,
cardiac arrest
,
cardiac failure
, cyanosis,
ECG changes, flushing, hypertension,
hypotension, ischaemia,
myocardial
ischaemia
, palpitations, peripheral vascular
disorder,
shock
.
Eye:
altered vision, conjunctivitis, eye
disorder, eye pain.
GI:
chelitis, diarrhoea, dysphagia, glossitis,
nausea, vomiting.
GU:
incontinence,
contrast medium–
induced nephrotoxicity
,
renal failure
,
urinary urgency.
Musculoskeletal:
asthenia.
Psychiatric:
confusion.
Respiratory:
apnoea
, asthma, cough,
dyspnoea, laryngeal oedema, pharyngitis,
rhinitis, sinusitis, upper respiratory tract
infection.
Skin:
angio-oedema
, erythema, hirsutism,
injection site pain, pruritus, rash, urticaria.
Other:
anaphylactic reaction
, fever,
hypersensitivity reactions, iodism, malaise,
pyrexia.
Interactions
Drug-drug.
Metformin/biguanides:
Potential
transient impairment of renal function
with possible lactic acidosis. Should be
discontinued 48 hours prior to procedure.
Interleukin-2:
Increased risk of delayed
reactions. Monitor closely.
Beta blockers:
Atypical anaphylaxis. Monitor
closely.
Neuroleptics and phenothiazine derivative
antidepressants:
Reduce seizure threshold.
Should be discontinued 48 hours prior to
and not resumed for 24 hours following
procedure.
Nephrotoxicdrugs:
Administration shouldbe
delayed until media has cleared the body.
Drug-lifestyle.
Alcohol:
Possibility of
development of CNS disorders. Exercise
caution.
Drugs of addiction:
Possible reduced seizure
threshold. Exercise caution.
Contraindications
Contraindicated in individuals with known
hypersensitivity to the preparation or
a history of serious hypersensitivity to
iomeprol, in those with acute inflammation
