Index
1215
cystic lesions of, 1035, 1035
f
disorders of, 1035–1036,
1035
f
, 1037
f
follicle development and ovu-
lation, 1022
f
, 1023–1024
hormone production,
1020–1023
neoplasms of, 1036, 1037
f
polycystic ovary syndrome,
1035–1036
Overflow incontinence, 665
Overweight.
See
Obesity
Oxidative phosphorylation, 9
Oxidative stress, 40–41, 46
Oxygen
delivery of, for wound healing,
83–84
transport of, 530–533,
532
f
–534
f
Oxygen-hemoglobin dissociation
curve, 531, 533–534, 534
f
Oxygen therapy
for COPD, 582
for heart failure, 498
hyperbaric, for wound healing,
83–84
Oxyhemoglobin, 530
p35 tumor-suppressor gene,
activation of, 7
Pacinian corpuscle, 858, 1145
PAD.
See
Peripheral arterial
disease
PAF.
See
Platelet-activating factor
Paget disease, 1046, 1117–1118,
1118
f
PAG region.
See
Periaqueductal
gray region
PAH.
See
Pulmonary arterial
hypertension
Pain, 860–868
acute, 865–866, 866
t
back, 894–896
brain centers and, 862–863
in children, 875–876
chronic, 865–867, 866
t
cutaneous, 864
deep somatic, 864
in elderly, 876–877
head.
See
Headache
management of, 867–868
mechanisms of, 861, 861
f
modulation of, 863–864
neuropathic, 869–870
pathways of, 861–864, 863
f
phantom limb, 871–872
referred, 864–865, 865
f
sensitivity to, alterations in, 869
temporomandibular joint, 875
theories of, 860–861
types of, 864–867
visceral, 864
Pain fibers, 862
Painful bladder syndrome, 670–671
Paleolayer, of white matter, 835
f
Paleospinothalamic tract, 857
PAMPs.
See
Pathogen-associated
molecular patterns
Panacinar emphysema, 580, 580
f
Pancreas
cancer of, 750
disorders of, 745, 746
f
, 748–750
glucose control by, 794, 795
f
transplantation of, 810
Pancreatic polypeptide, 794
Pancreatitis, 748–750
Paneth cells, 688, 688
f
Pannus, 1120, 1121
f
Papanicolaou smear, 148
Papillary dermis, 1144–1145
Papillary necrosis, 629
Papilloma, 130, 131
t
Papillomatosis, 166
PAPP-A.
See
Pregnancy-
associated plasma protein A
Papule, 1148, 1149
f
, 1160
Papulosquamous dermatoses,
1164–1166, 1165
f
–1166
f
Paracrine action, of hormones,
754, 755
f
Paradoxical movement, 521
Paralysis, 887, 887
f
Paralytic strabismus, 972
f
, 973
Paraneoplastic syndromes, 134,
145–146, 146
t
Paraphimosis, 1012
Paraplegia, 887, 887
f
Parasites, 305
Parasitic relationship, 298
Parasympathetic nervous system,
848
f
, 849
t
, 850
airways and, 520
in bladder control, 658–659,
659
f
in gastrointestinal system,
680–682, 682
f
–683
f
neurotransmission in, 851,
851
f
Parathyroid hormone (PTH)
in bone formation and metab-
olism, 1069, 1069
t
, 1072
f
in calcium balance regulation,
181–183, 182
f
disorders of, 189–190
with CKD, 646–647
in magnesium balance regula-
tion, 187–188
recombinant, 1114–1115
Parenchymal tissues, 71
in neoplasms, 130
Parietal layer, 568
Parietal lobe, 842, 843
f
Parietal pericardium, 465
Parietal peritoneum, 678
Parkinson disease, 899–901, 900
f
Paroxysmal nocturnal dyspnea,
494
Partial pressure, 520
Partial seizures, 945
c
Passive immunity, 340
Patella, subluxation and disloca-
tions of, 1082
Patellofemoral pain syndrome,
1082–1083, 1082
f
Patent ductus arteriosus, 475–477,
476
f
Pathogen-associated molecular
patterns (PAMPs), 327
Pathogens, 298
Pathogen virulence, in UTI,
667–668
Pathologic calcifications, 35, 35
f
Pathologic stress fractures, 1084
Pattern recognition receptors
(PRRs), 327
Pattern theory, of pain, 860
PCI.
See
Percutaneous coronary
intervention
PCOS.
See
Polycystic ovary
syndrome
PCR.
See
Polymerase chain reaction
Pedigree, 98
Pelvic inflammatory disease
(PID), 1030, 1030
f
Pelvic nerve, 658
Pelvic pain syndrome, chronic,
1007–1008
Pemphigus, 27
Pendrin, 776
Penetrance, 98
in congenital disorders, 108
Penetration, of infectious agents,
306
PE neurons.
See
Pharyngeal effer-
ent neurons
Penile erection, 997–998
dysfunction of, 998–999, 1014
Penis
disorders of, 1000–1002
neoplasms of, 1001–1002
Penumbra, ischemic, 933
Pepsin, 691
Pepsinogen, 691
Peptic ulcer disease, 703–704, 703
f
Peptidoglycan, 300
Percutaneous coronary interven-
tion (PCI), for myocardial
infarction, 453, 453
f
Percutaneous umbilical cord
blood sampling, 126
Perfusion, 528–529
in respiration, 565–566
ventilation matching with,
529, 529
f
, 594
Periaqueductal gray (PAG)
region, 863–864
Periarticular calcifications, 647
Pericardial effusion, 466–467, 467
f
Pericarditis
acute, 465–466
constrictive, 467
myocardial infarction and, 454
Pericardium, 382, 383
f
–384
f
disorders of, 465
c
, 465–467
Perichondrium, 1064
Perilymph, 980
Perimenopause, 1040
Perimysium, 24, 24
f
Perineurium, 824, 892
Perinuclear space, 3, 4
f
Periosteum, 1065–1066, 1065
f
Periotic fluid.
See
Perilymph
Peripartum cardiomyopathy, 471
Peripheral arterial disease (PAD),
415
Peripheral chemoreceptors, 536
Peripheral circulation.
See
Systemic circulation
Peripheral cyanosis, 566
Peripheral nervous system (PNS),
27, 821, 822
f
longitudinal tracts of, 835–
836, 835
f
–836
f
, 835
t
neuroglial cells of, 823–824,
824
f
segmental organization of,
831–836, 831
f
–832
f
,
833
t
–834
t
, 835
f
–836
f
Peripheral neuropathies,
892–896.
See also specific
neuropathy
flaccid bladder and, 663
Peripheral proteins, 2, 3
f
Peripheral tolerance, 354–356
Peripheral vascular disorders,
415–417
Peristaltic movements, in small
intestine, 684, 685
f
Peritoneal cavity, 678
Peritoneal dialysis, for CKD,
650–651, 651
f
Peritonitis, 716–717
Peritubular capillaries, 601
f
, 602
Permanent tissues, 73
Peroxisomes, 6
Petit mal seizures.
See
Absence
seizures
Peyronie disease, 1000–1001,
1001
f
pH
calculation of, 193, 194
f
primary v. compensatory
changes in, 196, 196
t
regulation of, 191
f
, 193–195,
612
Phagocytic disorders, 83–84
Phagocytosis, 5, 5
f
, 15–16
in inflammatory response,
55–56
Phagolysosome, 5, 5
f
Phagosome, 5, 5
f
, 15–16
in inflammation, 55–56
Phalen maneuver, 893
Phantom limb pain, 871–872
Pharyngeal efferent (PE) neurons,
833
f
, 835
Pharyngeal phase, of swallowing,
681, 684, 684
f
Pharyngoesophageal sphincter,
677
Phenotype, 98, 107
Phenylketonuria (PKU), 110–111
Pheochromocytoma, 428
Pheomelanin, 1143–1144
Philadelphia chromosome, 137,
250–253, 250
f
Phimosis, 1012
Phosphate buffers, 195
Phospholipids, in cell membrane,
2–3
Phosphorus
CKD and, 649–650
imbalance of, with CKD,
646–647
Phosphorus balance, 181
disorders of, 185–187
regulation of, 185–186
Photopic vision, 962
Photosensitivity, drug-induced,
1168
Physical maps, in genetics,
100–101
Physiologic dead space, 528
Physiologic reserve, for adapta-
tion, 213
Physiologic shunt, 529
Pia mater, 837, 838
f
–839
f
, 844,
844
f
Pick disease.
See
Frontotemporal
dementia
PID.
See
Pelvic inflammatory
disease
PI genes.
See
Protein inhibitor
genes
Pigmentary skin disorders,
1148–1150, 1149
f
Pigmented birthmarks, 1178,
1178
f
